A Zinc Finger Protein: Xenopus laevis Apex2 C-terminal Znf-GRF Domain



X-ray Crystal Structure
Reference: PDB Code 5u6z:
Wallace, B.D., Berman, Z., Mueller, G.A., Lin, Y., Chang, T., Andres, S.N., Wojtaszek, J.L., DeRose, E.F., Appel, C.D., London, R.E., Yan, S., Williams, R.S. , Proc. Natl. Acad. Sci. U.S.A. Vol 114 2017, p. 304-309


From the Abstract "The Xenopus laevis APE2 (apurinic/apyrimidinic endonuclease 2) nuclease participates in 3'-5' nucleolytic resection of oxidative DNA damage and activation of the ATR-Chk1 DNA damage response (DDR) pathway via ill-defined mechanisms."








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