Joseph W. Chihade

Please follow these links for more information:

• My education and research experience
• Courses taught at Carleton College

Teaching Interests:

Organic Chemistry, Biological Chemistry.

Research Interests:

My research interests are in the broad areas of protein-RNA interactions and RNA structure. These areas lie at the intersection of biology and chemistry, and encompass wide variety of scientific perspectives. These range from the "biological" questions of which proteins interact with particular RNAs, what the consequences of these interactions are to the living cell, and how particular interactions evolved, to the more "chemical" questions of how a specific functional group influences a macromolecular interaction or changes the structure of a macromolecule, and how a simple chemical reagent can be used to elucidate biological function.

Currently research in the lab is focused on two projects: characterizing substrate recognition of alanyl-tRNA synthetases which aminoacylate the highly unusual tRNAs found in animal mitochondria and developing tools for creating RNA-based enzyme mimics using specific RNA modifying enzymes and carbodiimide reagents.

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